Biotechnology Journal International

Keratin is an insoluble and protein-rich epidermal material found in feathers, hair, wool and skin but it poses a challenge in environmental waste management because of its resistance to degradation. Particularly, keratinolytic bacteria and fungi, have demonstrated the ability to break down keratin into simpler components, offering solutions for waste management and biotechnological applications. Despite their resistant structure, keratin wastes can be degraded by various microorganisms through the secretion of keratinases, which are excellent enzymes for several applications including detergents, fertilizers, leather and textile industry. In an attempt to isolate keratinolytic microorganisms that can reach commercial values as keratinase producers this project aims to delve into the mechanisms employed by various microbial species in the degradation of keratinaceous materials. Through genomic and proteomic analysis, we explore the enzymatic pathways and key proteins involved in keratin degradation.

This investigation involves morphological examination to identify and characterize the keratinolytic microorganisms from diverse ecological aspects. Also, the project focuses on the practical implications of keratin degradation. Understanding the enzymatic processes underlying keratin breakdown could pave the way for the design of innovative biocatalysts and bioremediation strategies for the efficient utilization of keratin-rich waste streams.