Antibiotic/Antibacterial activity of Vitex negundo, Duranta repens, Acorus calamus and Piper nigrum
Burhan M. Padder *
Department of Botany, University of Kashmir Hazratbal Srinagar 190006, India
Shagufta Yasmeen
Department of Biotechnology and Microbiology, Karnatak University Dharwad. 580003, India
Mudasar Ganaie
Department of Botany, University of Kashmir Hazratbal Srinagar 190006, India
*Author to whom correspondence should be addressed.
Abstract
Antibiotic/Antibacterial activity of Vitex negundo, Duranta repens, Acorus calamus and Piper nigrum
Plants produce a diverse nature of secondary metabolites having different biological activity. Some of these chemicals exhibit antimicrobial activity. In the present study the plant extracts of Vitex negundo, Duranta repens, Acorus calamus and Piper nigrum were tested individually as well as synergistically for antibiotic/ antibacterial activities. It was found that the plant extract of V. negundo was most effective against both S. mutans MTCC 890(MIC value 0.37) and P. aeruginosa MTCC 0741 (MIC value 0.75) than other three extracts of D. repens, P. nigrum, A. calamus whereas the plant extract of P. nigrum was least effective against both S. mutans MTCC 890(MIC value 3.12) and P. aeruginosa MTCC 0741(MIC value 6.25).
Keywords: Antimicrobials, plant extracts, secondary metabolites, individual, synergistic activity